Introduction to Sotalol IV
Initiate and discharge patients in less than 1 day* with Sotalol IV.1
Sotalol IV is a faster way to initiate or uptitrate sotalol treatment compared to oral sotalol alone. Just one hour1 of Sotalol IV infusion can achieve the same maximum serum concentration as three days2 of oral sotalol. This faster protocol can lead to patients being discharged from the hospital within 20 to 24 hours,* potentially saving time and resources.
Learn more about Sotalol IV
- Video
Case Study: Advantages of Using Sotalol IV as a Loading Dose
Brad Knight, MD discusses the advantages of Sotalol IV at his practice for both patients and nursing staff. Dr. Knight's appearance in this video was sponsored by AltaThera
- Video
How to Administer a Loading Dose of Sotalol IV in Adults
This video provides a comprehensive, step-by-step guide to the recommended administration of Sotalol IV as a loading dose in adults, including important steps to complete before, during, and after the drug infusion.
- Research
Expedited Loading with Intravenous Sotalol and Mobile ECG Monitoring – Primary Results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry.
Steinberg BA, Deering TF, Holubkov R, et al. Expedited Loading with Intravenous Sotalol and Mobile ECG Monitoring - Primary Results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry. Poster Presented at Heart Rhythm Society 2023; May 19 -21, 2023; New Orleans, LA.
Download an introduction to Sotalol IV.
One document containing the basics of dosing, ordering, and more.
Additional Intro Resources
- Video
Considerations When Implementing Sotalol IV In Your Practice
Brad Knight, MD discusses some considerations when integrating Sotalol IV into your hospital workflow. Dr. Knight's appearance in this video was sponsored by AltaThera.
- Video
Case Study: Advantages of Using Sotalol IV as a Loading Dose
Brad Knight, MD discusses the advantages of Sotalol IV at his practice for both patients and nursing staff. Dr. Knight's appearance in this video was sponsored by AltaThera
- Video
How to Administer a Loading Dose of Sotalol IV in Adults
This video provides a comprehensive, step-by-step guide to the recommended administration of Sotalol IV as a loading dose in adults, including important steps to complete before, during, and after the drug infusion.
- Video
Case Study: Achieving success when implementing Sotalol IV
We explored what success looked like when implementing a Sotalol IV protocol at an institution with Benjamin Steinberg, MD, MHS, FACP, FACC, FHRS
- Video
Review of a Sotalol IV Retrospective Study Presented at ACC.24
We explored a retrospective study on Sotalol IV presented at ACC.24 by Keturah DelGrosso, PharmD, BCPS
- Video
An Overview of the Sotalol IV PEAKS Registry
We discussed the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry with T. Jared Bunch, MD.
- Video
Trends in AFib Practice Patterns
We sat down with T. Jared Bunch, MD to discuss trends in atrial fibrillation and practice patterns in usage of intravenous sotalol.
- Research
Expedited Loading with Intravenous Sotalol and Mobile ECG Monitoring – Primary Results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry.
Steinberg BA, Deering TF, Holubkov R, et al. Expedited Loading with Intravenous Sotalol and Mobile ECG Monitoring - Primary Results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry. Poster Presented at Heart Rhythm Society 2023; May 19 -21, 2023; New Orleans, LA.
- Research
Implementation of an intravenous sotalol initiation protocol: Implications for feasibility, safety, and length of stay.
Liu AY, Charron J, Fugaro D, et al. Implementation of an intravenous sotalol initiation protocol: Implications for feasibility, safety, and length of stay. J Cardiovasc Electrophysiol. 2023; 34:502‐506. doi:10.1111/jce.15819
Want to hear more?
Explore next steps to use Sotalol IV at your institution.
*Discharge depends on clinical evaluation, renal function, and response to therapy. Patients with GFR ≥ 60 mL/min may be discharged within 20-24 hours; however, timing may vary.
REFERENCES
1 Sotalol IV [package insert]. Chicago, IL: AltaThera Pharmaceuticals; 07/2025.
2 BetaPace AF (sotalol hydrochloride) [Full Prescribing Information]. Zug, CH: Covis Pharma; 06/2023.