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Intravenous rhythm control for pediatric patients

Sotalol IV offers benefits for pediatric drug therapy.

Efficiency

Fast Onset

Facilitates timely evaluation of therapeutic response, to support clinical decision-making

Linear Kinetics

Linear Kinetics

Allows for predictable dosing, simplified dose adjustment, and smooth transition to oral therapy

Half-Life

Short Half-Life

Enables prompt discontinuation and transition to alternative treatment strategies

Intravenous infusion

Intravenous Infusion

Offers controlled delivery and less variability in absorption compared to oral dosing alone

Soty pointing

Sotalol is an antiarrhythmic indicated for...

  • The maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter (AFIB/AFL)) in adults and pediatric patients with highly symptomatic AFIB/AFL who are currently in sinus rhythm.  
    Limitations of use: Avoid use in patients with minimally symptomatic or easily reversible AFIB/AFL.

  • The treatment of documented, life-threatening ventricular arrhythmias, such as sustained ventricular tachycardia in adult and pediatric patients.
    Limitations of use: Sotalol has not been shown to enhance survival in patients with life-threatening ventricular arrhythmias.

Heart pointing

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REFERENCES
1 Sotalol IV [package insert]. Chicago, IL: AltaThera Pharmaceuticals; 07/2025.
2 BetaPace AF (sotalol hydrochloride) [Full Prescribing Information]. Zug, CH: Covis Pharma; 06/2023.

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Highlights of Prescribing Information

Boxed Warning, Indications, and Important Safety Information

WARNING: LIFE THREATENING PROARRHYTHMIA

Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation. To minimize the risk of drug induced arrhythmia, initiate or uptitrate intravenous sotalol in a facility that can provide continuous electrocardiographic monitoring and cardiac resuscitation [see Dosage and Administration (2.3) and Warnings and Precautions (5.1)].
Do not initiate intravenous sotalol therapy if the baseline QTc is longer than 450 ms. If the QTc prolongs to 500 ms or greater, reduce the dose or discontinue.