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How to Administer a Loading Dose of Sotalol IV in Adults

Video overview of important information about using Sotalol IV

Description

This video provides a step-by-step guide to the latest recommended use of Sotalol IV as a loading dose in adults for the initiation or uptitration of sotalol therapy, including important steps to complete before, during, and after the drug infusion.

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References

  1. Sotalol IV [package insert]. Chicago, IL: AltaThera Pharmaceuticals; 07/2025. sotaloliv.com/pi
  2. BetaPace [package insert]. Zug, Switzerland: Covis Pharma; 2023.

Will Reeves’ appearance in this video was sponsored by AltaThera.

SIV-VID-002.1-072025

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Highlights of Prescribing Information

Boxed Warning, Indications, and Important Safety Information

WARNING: LIFE THREATENING PROARRHYTHMIA

Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation. To minimize the risk of drug induced arrhythmia, initiate or uptitrate intravenous sotalol in a facility that can provide continuous electrocardiographic monitoring and cardiac resuscitation [see Dosage and Administration (2.3) and Warnings and Precautions (5.1)].
Do not initiate intravenous sotalol therapy if the baseline QTc is longer than 450 ms. If the QTc prolongs to 500 ms or greater, reduce the dose or discontinue.